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CAD and Platelet Dysfunction


Treatment of Acute Coronary Syndrome (ACS) involves many of the platelet modulating drugs such as Aspirin, GPIIb/IIIa inhibitors.

Primary Prevention of Coronary Artery Disease includes Aspirin. Secondary Prevention of CAD includes Aspirin.

Though the current models for atherosclerosis does not revolve around platelet abnormalities: the question raised here is: 1. Are there any platelet speicific pathophysiology that predispose one to have ACS. 2. Are there any interventions (other than Aspirin) that are specifically related to platelets for primary/secondary prevention.

We will first review: 1. Platelet physiology 2. Atherosclerosis physiology




Clinical PresentationEdit




Associated Diseases and complicationsEdit


Further research suggestions/DiscussionEdit

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